Brain-Initiative

Brain-Initiative funding pages collect matching grants, scholarships, benefits, fellowships, and other programs from the FindMyMoney.App directory. Use this page to compare current opportunities, then verify deadlines and eligibility on the official source before applying.

BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)

Supports dissemination-focused, collaborative neuroscience resource development and distribution to strengthen the BRAIN Initiative infrastructure through no-more-than-5-year cooperative-Agreement projects.

Status: Rolling Type: Grant Deadline: Rolling or ongoing Location: United States

RFA-DA-27-004: BRAIN Initiative Theories, Models and Methods (R01, No Clinical Trials)

A 2026/2027 NIH BRAIN Initiative NOFO that funds computational, statistical, and data science tool development for analyzing complex multi-scale neural data with up to 15 awards per year from a $6M annual set-aside.

Status: Open Type: Grant Amount: NIH anticipates $6M/year for up to 15 awards Deadline: Oct 6, 2026 Location: United States

RFA-DC-27-004: BRAIN Initiative Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61)

NIH BRAIN Initiative award for exploratory human neuroscience using direct intracranial recording with or without stimulation, with clinical trials not allowed, up to $700,000 in direct costs per year and a 3-year maximum project period.

Status: Open Type: Grant Amount: Estimated $6M total costs for approximately 5 awards per receipt date Deadline: Feb 11, 2027 Location: United States

RFA-EY-25-001 (Historical Reference): BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21)

Historical reference for the expired NIH BRAIN Initiative R21 notice RFA-EY-25-001, which supported early-stage technologies for neural recording and modulation. NIH has not listed a successor cycle on the verified notice page.

Status: Historical Type: Grant Amount: NIH intended an estimated 10 awards per fiscal year, totaling $3-$4 million in new awards per … Deadline: Historical reference Location: United States and International

RFA-MH-26-120: BRAIN Initiative Reagent Resources for Brain Cell Type-Specific Access (U24)

NIH’s BRAIN Initiative cooperative agreement funds facilities that produce and distribute brain cell type-specific access and manipulation reagents for neuroscience users.

Status: Open Type: Grant Deadline: Jun 15, 2027 Location: United States

RFA-MH-26-140: BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)

NIH BRAIN Initiative U01 cooperative agreement for novel sensor technologies and bioelectronic devices that synchronize real-time behavioral data with neural recordings; an estimated $10 million is intended to fund 6-8 awards for each receipt date.

Status: Open Type: Grant Amount: Estimated $10 million total for 6-8 awards per receipt date; application budgets are not limited Deadline: Jun 15, 2027 Location: United States and Non-U.S. eligible entities and non-domestic components of U.S. organizations

RFA-MH-26-170: BRAIN Initiative - Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01)

NIH BRAIN Initiative reissue NOFO for R01 projects that develop and validate high-impact tools for precise, cell- and circuit-specific neuroscience research without clinical trials.

Status: Open Type: Grant Amount: $8,000,000 total, 6-9 awards expected Deadline: Feb 8, 2027 Location: United States and International (foreign entities eligible)

RFA-NS-24-031: BRAIN Initiative Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18)

NIH’s BRAIN Initiative R18 NOFO supports proof-of-concept development of novel CNS recording and modulation technologies on a path toward human studies, with recurring 2026/2027 NIH submission windows.

Status: Open Type: Grant Amount: Estimated $8,000,000 total (5–7 awards); budgets not limited Deadline: Jan 28, 2027 Location: United States

RFA-NS-25-017: BRAIN Initiative—Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System

Historical NIH BRAIN Initiative U01 funding opportunity for optimizing instrumentation and device technologies for neural recording and modulation. The final receipt date was June 15, 2026, and the NOFO expired June 16, 2026; no successor cycle is announced on the official notices reviewed.

Status: Historical Type: Grant Amount: Estimated $10,000,000 per year for 15–20 awards Deadline: Historical reference Location: United States

RFA-NS-25-021: BRAIN Initiative Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3)

NIH BRAIN Initiative cooperative agreement to accelerate translational development of recording and modulation devices for CNS disorders through milestone-driven UG3/UH3 funding and small clinical studies requiring FDA IDE pathways.

Status: Open Type: Grant Amount: NIH anticipates $10M per year; estimated 5 to 7 awards. UG3: up to $500,000 direct costs/year Deadline: Sep 28, 2026 Location: United States